22 Temmuz 2019 Pazartesi

The Ultimate Guide To Dexamethasone

Dexamethasone is a corticosteroid that is used to treat different heath conditions such as skin diseases, allergic disorder, asthma, brain swelling, rheumatic arthritis and problems.

This drug comes in different trade names such as Decadron, Dexasone, Diodex, Hexadrol, Maxidex, DexPak, Zema-Pak, etc.. It decreases the defensive response of your system and reduces symptoms. It can be administered with antibiotics to treat tuberculosis.

Dexamethasone is administered to the body system through the following means:

Intravenous Therapy: When the medicine in liquid form, it's administered to the body by delivery through the vein with the aid of injections or as drips. This mode of administration is regarded as the fastest as it goes directly to the bloodstream.

Intramuscular treatment: Otherwise known and abbreviated as IM. This drug delivery system is done by the aid of injection to the muscle.

Subcutaneous Injection Therapy: is one of the many system of drug administration. It is abbreviated as SC and can be used to administration dexamethasone through the subcutaneous layer of the skin.

Oral Administration: This entails administering dexamethasone through the mouth.

INGREDIENTS

Dexamethasone Tablets USP usually contain either 0.5 mg, 0.75 mg, 1.5 mg, 2 mg, 4 mg, or 6 mg of dexamethasone USP. Each tablet also contain some inactive ingredients such as magnesium stearate, lactose, monohydrate, sugar, starch, FD&C Red, FD&C Yellow, Yellow Iron Oxide, D&C Yellow, and FD&C Blue.


Dexamethasone Oral Solution USP is formulated for oral administration comprises 05.5 mg per 5 ml of dexamethasone USP. This oral solution contains some inactive ingredients such as propylene glycol, sorbitol solution, propylparaben, anhydrous citric acid, glycerin, disodium edetate and water.

USES OF DEXAMETHASONE/PROS

Dexamethasone has various uses in anti inflammatory diseases, cancer, endocrine treatment, pregnancy, higher altitude illnesses, nausea and vomiting, sore throat, and veterinary applications.

Veterinary Uses:

Dexamethasone is combined with clotrimazole and marbofloxacin with a brand name AURIZON as a remedy for acute earing infections especially in puppies.

Dexamethasone combined with dichlormethiazide can be used in the treatment of general bruising and swelling distal limbs in horses.

Anti-inflammatory diseases:

A single dose of dexamethasone in children reduces the swelling of the airway which in turns improves breathing and reduced discomfort. To put it differently, can be used for treating CROUP in children. Dexamethasone given in a high dose serves as a counteract to allergic anaphylactic shock, Dexamethasone intravitreal steroid implant has been approved by the Federal dental agency for the treatment of ocular conditions like diabetic macular edema, central retinal vein occlusion, and uveitis, dexamethasone is present in ear drops, eye drops particularly after eye surgery and present in nasal sprays. Dexamethasone is used to treat inflammatory and autoimmune conditions like rheumatoid arthritis, Idiopathic thrombocytopenic purpura. Dexamethasone is given before and or after dental surgeries like the elimination of the wisdom tooth. Dexamethasone may also be treated before antibiotics in the event of bacterial meningitis to reduce inflammatory response to the killed bacterias.

Cancer:

In brain tumors, dexamethasone can be used to suppress the development of edema which can compress other brain structures if not attended to, dexamethasone can be utilised as an immediate chemotherapeutic agent for the treatment of multiple myeloma.

Pregnancy:

Pregnancy complications may occur like premature delivery, but with the use of dexamethasone, it helps correct premature delivery by helping in the maturation of the fetus' lungs.

Nausea and vomiting

Individuals who've had surgery experience nausea and vomiting. Administration of dexamethasone intravenously is effective for preventing nausea and vomiting from recurring.

SIDE EFFECTS/CONS

Dexamethasone, like every other drugs has side effects they give. The Normal side effects from the ingestion of dexamethasone includes

Dizziness

Stomach upset

Sore throat

Headaches

Trouble in sleeping

Increase in appetite

Weight gain

Acne


But if the below listed serious side effects take place, contact your doctor when you notice

Increased thirst and urination

Signs of infection like fever

Slow, fast or irregular heartbeat

Black stool,

Heartburns

Bone pain

Abdominal pain

Mental changes

Bleeding

Seizures


Precautions

If you have a fungal infection or allergic to this medication, please do not take it. Before taking dexamethasone, tell your doctor or pharmacist if you have:

Malaria

Thyroid disorder

Liver disease

Glaucoma or cataracts

Tuberculosis

Osteoporosis

Mental illness

Depression

Liver disease

Heart failure

High blood pressure

Herpes infection of the eyes

Diabetes

This medication may mask signs of infection or put you at greater risk of developing very serious ailments. Report any injuries or signs of infection (e.g., persistent sore throat/fever/cough, pain during urination, muscle aches) that occur during treatment.


This medication may slow down a child's development if used for quite a while. Consult the doctor or pharmacist for more details. See the physician regularly so your child's height and growth could be checked.

This drug may pass into breast milk and may have undesirable effects on a nursing infant. Consult your doctor before breast- feeding.

OVERDOSE

An overdose of this medication doesn't pose any life-threatening issues. Long term use of high does can lead to thinning skin, increased acne or facial hair, loss of interest in sex, menstrual problems and impotence.


DRUGS THAT AFFECT DEXAMETHASONE

It's not a good safe to use some specific drugs in exactly the same time since they pose a great deal of risks. Ensure you tell your doctor about all the drugs you are using before taking dexamethasone for example;

Insulin or diabetes medications

Birth control pills or hormone replacement therapy

Blood thinner -- Coumadin, Jantoven

Antibiotic or antifungal medicine

Medication to treat dementia or Parkinson disease

CONCLUSION

The activity of the world health organization in tagging dexamethasone as an important drug in the health care field has revealed dexamethasone to be of relevance to the health of man and studies showing that excess dexamethasone can induce hypertension through various mechanisms demonstrate that where there is great, there's also bad. Moderation is the key to ensuring that more good than bad is what's gotten from this drug. Following the doctor's prescription strictly rather than self-medicating will also help to make dexamethasone us be of more good than bad.


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The Ultimate Guide To Dexamethasone

Dexamethasone is a corticosteroid that is used to treat different heath conditions such as skin diseases, allergic disorder, asthma, brain s...